Multiple sclerosis (MS) is almost always accompanied by fatigue, a severe tiredness that is described by the vast majority of patients as the most burdensome symptom.
In a recent study, a research group led by Stefan Seidel from the Department of Neurology at MedUni Vienna in Austria and AKH Vienna established light therapy as a promising non-drug treatment option: patients participating in the study showed a clear improvement after just 14 days of use.
The research results were recently published in the Multiple Sclerosis Journal—Experimental, Translational and Clinical.
For the first time, Stefan Seidel's research team relied not only on surveys but also on objective measurements when selecting test subjects. For example, sleep-wake disorders were ruled out in the 26 participating MS patients, mainly with the help of various sleep-medical examinations.
“For example, we have ensured that MS patients with fatigue do not suffer from sleep apnea or periodic leg movements during sleep. Both are sleep disorders that can lead to fatigue in everyday life,” explains research leader Stefan Seidel.
Performance improvement
The subjects – all patients from the Department of Neurology at MedUni Vienna and AKH Vienna – were given normal, commercially available light sources for home treatment: half of the participants were given a daylight lamp with a brightness of 10,000 lux, the other half were given an identical lamp that emitted a red light through a filter with an intensity of <300 lux.
Fatigue is a severe form of tiredness that occurs in 75% to 99% of people with MS and is described as particularly distressing. Damage to the central nervous system caused by MS is thought to be the cause.
Promising and non-drug
In addition to behavioral measures such as regular rest breaks, there are currently several medications available to relieve fatigue, but several of these are accompanied by serious side effects.
The findings of our study show a promising non-drug therapeutic approach,” confirms Stefan Seidel. However, the results still need to be confirmed in a later study on a larger scale. The precise background of the positive effect of light therapy in MS patients will also be the subject of further scientific research.
SOURCE: Medicine
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